Sodium Salicylate BP Ph Eur USP Grade Manufacturers

Anmol Chemicals is the pioneer manufacturers of Sodium salicylate, Pharmaceutical Excipients Fragrance & Flavor chemicals in India. We offer Halal and Kosher Sodium salicylate made in an ISO9001, ISO22000 (FSSC22000) cGMP and GLP certified facility. Our group has several manufacturing facilities spread across the world, supported by toll manufacturers and representatives in UAE, Europe, Africa, USA, China and has several associated manufacturing facilities spread across India. All the Information on Physics, Chemistry, Applications, Uses and Technology on Manufacture of Sodium salicylate is in these pages.

The units have one or more of the certifications like FDA GMP, ISO 9001, ISO 22000, HACCP, REACH, Kosher & Halal

Pure Sodium Salicylate BP Ph Eur USP Grade Manufacturers

CAS number: 54-21-7
Einecs EC number: 200-198-0
Molecular formula: C7H5NaO3
Molecular weight: 160.11 g/mol

Sodium salicylate is a sodium salt of salicylic acid. It is used in medicine as an analgesic and antipyretic. Sodium salicylate also acts as non-steroidal anti-inflammatory drug (NSAID) and induces apoptosis in cancer cells and also necrosis. It is also a potential replacement for aspirin for people sensitive to it.

Application: Sodium salicylate, a white to pinkish white powder, is used for antiseptics preparations and as a preservative. In addition to its analgesic and antipyretic properties, it possesses keratinolytic properties and fungicidal properties. Itself and its derivatives are used in the treatment of hyperkeratotic, dandruff, ichthyosis and psoriasis as well as in the treatment of fungal skin infections such as tinea.

Sodium Salicylate BP Grade
Ph Eur
C7H5NaO3 -- 160.1 -- CAS Number 54-21-7
Action and use: Anti-inflammatory; analgesic.

DEFINITION
Sodium 2-hydroxybenzenecarboxylate.
Content: 99.0 per cent to 101.0 per cent (dried substance).

CHARACTERS
Appearance: White or almost white, crystalline powder or small, colourless crystals or shiny flakes.
Solubility: Freely soluble in water, sparingly soluble in ethanol (96 per cent).

IDENTIFICATION
First identificationıA, C.
Second identificationıB, C.
A. Infrared absorption spectrophotometry.
B. Solution S (see Tests) gives the reactions of salicylates.
C. It gives reaction (b) of sodium.

TESTS
Solution S: Dissolve 5.0 g in carbon dioxide-free water prepared from distilled water and dilute to 50 ml with the same solvent.
Appearance of solution: Solution S is clear and not more intensely coloured than reference solution BY6.
Acidity: To 20 ml of solution S add 0.1 ml of phenol red solution. The solution is yellow. Not more than 2.0 ml of 0.01 M sodium hydroxide is required to change the colour of the indicator to violet-red.
Chlorides: Maximum 200 ppm.
Sulphates: Maximum 600 ppm.
Heavy metals: Maximum 20 ppm.
Loss on drying: Maximum 0.5 per cent, determined on 1.00 g by drying in an oven at 105C.

Sodium Salicylate USP Grade
C7H5NaO3 --- 160.10
Benzoic acid, 2-hydroxy-, monosodium salt.
Monosodium salicylate --- [CAS Number 54-21-7].

Sodium Salicylate contains not less than 99.5 percent and not more than 100.5 percent of C7H5NaO3, calculated on the anhydrous basis.

Packaging and storage: Preserve in well-closed, light-resistant containers.
Identification: A solution (1 in 20) responds to the tests for Sodium and for Salicylate.
Water: not more than 0.5%.
Sulfite or thiosulfate: Add 1 mL of hydrochloric acid to a solution of 1.0 g in 20 mL of water, and filter the liquid: not more than 0.15 mL of 0.10 N iodine is required to produce a yellow color in the filtrate.
Heavy metals: Dissolve 2 g in 46 mL of water. Add, with constant stirring, 4 mL of 3 N hydrochloric acid, filter, and use 25 mL of the filtrate: the limit is 0.002%.

Sodium Salicylate Manufacturers

Anmol Chemicals
S-8, SARIFA MANSION, 2ND FLANK ROAD, CHINCHBUNDER, MUMBAI 400009, INDIA
TEL: (OFFICE) 91-22-23770100, 23726950, 23774610, 23723564 - FAX: 91-22-23728264

Exports to USA, Canada, UAE, Dubai, South Africa, Tanzania, Kenya, Nigeria, Egypt, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Europe Netherlands, Italy, Spain, Germany, Portugal, France, Malaysia, Indonesia, Thailand, Vietnam, Korea, Japan, etc.

Assay	98.5% min
Appearance	White to pinkish white powder
pH	5 - 6
Clarity & color of solution	Clear
Loss of drying %	0.50%
Heavy metals	20 max ppm
Chloride	200 max ppm
Sulphate	600 max ppm